6k for Footprint-Free mRNA iPSC Reprogramming Service - 3/20/2013


Allele biotechnology is now offering our custom mRNA iPSC reprogramming service for $6000.00. Our validated and published reprogramming protocol is completely feeder-free, xeno-free, and allows for rapid whole well iPSC generation. Characterization includes antibody staining for TRA-1-60, Nanog and SSEA3. The estimated time frame for our service is 6 - 8 weeks and you will receive your choice of 6 clones or bulk converted cells.


Clean - Completely feeder-free and xeno-free.

Footprint-Free - No risk of any safety hazard, biocontaminent issues, or genome modifications associated with viruses

Reliable - We use a validated and published method developed at Allele Biotechnology by the foremost experts int he field of mRNA reprogramming.

Cost Effective- iPSC reprogramming services can be costly, but now Allele is offering our unique footprint free service for a low cost at $6,000

Required Materials
Target fibroblasts, 1 vial of typical storage size, and indication of appropriate growth medium and conditions.

To inquire further about our service or initiate a project please email us at info@allelebiotech.com or give us a call at 800-991-7642


iPSC Reprogramming

Since 2006 when the ability to first create iPS cells was described, the technology has been sought after in research for its potential in a wide variety of applications. However, the most effective methods (lentiviral transmission of transcription factors) have had there own set of drawbacks associated with there use. Fortunately, in 2010, Warren et al. reported a novel, footprint-free method to reprogram human fibroblasts into iPSCs using messenger RNA. Through the combined efforts of Dr. Warren and the scientists here at Allele, we are excited to offer our feeder-free, xeno-free iPSC generation service utilizing a foot-print free mRNA protocol. More can be found about this technique in our latest paper "Feeder-Free Derivation of Human Induced Pluripotent Stem Cells with Messenger RNA" that was published in Scientific Reports (Nature Publishing Group).

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