Directed differentiation of both stem cells (iPS and Embryonic) and adult cells has been achieved recently through the addition of various factors. Below is a listing of differentiation targets, and the various factors required to achieve those targets (based on the current publications available). Factors that are linked to a product page have already been produced and are available for immediate purchase. Factors that are not hyperlinked can be requested, and will be made on demand at which point we will carry it in stock. The typical production time required is 1 to 2 weeks after we obtain the appropriate cDNA. Unlisted factors can also be requested, please email info@allelebiotech.com with your requests for both listed and unlisted factors.
Cell Type | Differentiation Factor |
iPSC | Oct 3/4 |
iPSC | Sox2 |
iPSC | c-Myc |
iPSC | Klf4 |
iPSC | lin28 |
iPSC | Nanog |
iPSC | Mir-302bcad/367 |
iPSC | Mir-302 |
iPSC | Mir-200c |
iPSC | Mir-369 |
Cardiomyocyte | Tbx5 |
Cardiomyocyte | Mef2c |
Cardiomyocyte | Gata-4 |
Cardiomyocyte | Mesp1 |
Cardiomyocyte | Mir-1-1 |
Neuron | Brn2 |
Neuron | Ascl1 |
Neuron | Mytl1 |
Neuron | Zic1 |
Neuron | Lmx1a |
Neuron | FoxA2 |
Neuron | NeuroD2 |
Neuron | NeuroD1 |
Neuron | Mir-9 |
Neuron | Mir-124 |
Neuron | Lhx3 |
Neuron | Ngn2 |
Neuron | Hb9 |
Neuron | Isl1 |
Hepatocytes | Gata-4 |
Hepatocytes | HNF1-alpha |
Hepatocytes | HNF4-alpha |
Hepatocytes | Foxa1 |
Hepatocytes | Foxa2 |
Hepatocytes | Foxa3 |
Beta-Cell | Ngn3 |
Beta-Cell | Pdx1 |
Beta-Cell | MafA |
Beta-Cell | VP16 |
Blood Progenitor | Gata1 |
Blood Progenitor | Gata2 |
Blood Progenitor | Gata3 |
Blood Progenitor | Gata-4 |
Myocytes | MyoD |
Myocytes | Mir-1-1 |
Myocytes | Mir-133 |
Myocytes | Mir-143 |
Myocytes | Mir-145 |
Osteoblast | Mir-2861 |
Osteoclast | C-fos |
Osteoclast | Mitf |
Osteoclast | Tfe3 |
Endothelium | Runx1 |
Endothelium | C-Myb |