[100 ug]
Neurogenin-2 (Ngn2; encoded by the NEUROG2 gene) is a basic helix–loop–helix (bHLH) transcription factor that directs early neural lineage specification. It functions as a proneural regulator, promoting neuronal differentiation by activating downstream neurogenic programs and suppressing alternative fates. Ngn2 is critical for the development of multiple regions of the central nervous system, where it influences progenitor cell commitment and neuronal subtype identity.